I have found cathedral interiors are lit well enough to support a quality camera body/F4 lens like you have.
Remember, tours move rather briskly and there is little time to swap out lenses, and you don't want to be "That Guy/Gal" holding up the tour causing others to miss seeing the sights.
In such cases, I would shoot interiors at F4 (wide open), use the reciprocal shutter speed rule (1 over the length of the lens, 1/60 sec for the 12-70mm lens), and set the ISO setting to "Auto".
Now you "have the shot" and it will not be blurry (Shutter Speed - set too slow) and your Depth of Field will be good using F4.
Important to note that "Noise" is "Fixable" and "Blur" and "Focus" are not.
When you return home you may correct "Noise" in post-processing using PhotoShop, Topaz Photo AI, or another quality specialty editing program that will DeNoise/Sharpen your treasures.
Best Wishes for safe travels, take many pics and share your best with us here on UHH.
Remember to always . . . .
Smile,
JimmyT Sends
PS: Practice in any dimly lit place BEFORE you go to see what to expect and correct accordingly.
Also, consider the "P" and "A" settings on your camera body as they can be of great help in Lo-Light settings for such an Expen$ive Trip.
I expect to be severly Flogged for the previous comment, sigh.
I have found cathedral interiors are lit well enou... (