My monitors are color calibrated monthly, and when I view this I see a distinctly red color cast, and Photoshop's info panel also shows more red than the other two colors. Since the original was black and white, my guess is that this RGB image had a color cast introduced in the scanning process.

I don't know how you're editing this image, but in Photoshop I would just use a Black and White adjustment layer to eliminate the cast. Then you can fiddle with the color sliders to adjust your tones, if desired. In this example, after applying the adjustment layer, the info panel shows that the sampled area is neutral. This is the same no matter where the sample is taken.

2049 Pix x 1537 pix is the original dimensions and 72 PPi this is the file i received from the client. they want a very large print 48x60. I have tried a varity of things in PS image size> changing the dimensions and or the resolution and or the resample options if i increase the dimensions the resoltion drops to around 42PPi when i increase the resolution and the dimension size the screen preview shows a fairly blurry image at 100%
Any best practice ideas out there in hedgehog landia? _ Kurt