In my experience, there are very real differences between computers made for home use and those made for business use, particularly for laptops. Although there are exceptions, the "business" models generally are constructed in a way that allows for the case to be opened and reassembled without the risk of breaking snap-together fasteners. They are generally more expandable or upgradeable...once you do get them open. the design allows for more reconfiguration. Home models may have permanently soldered memory chips and hard drives, while business models will generally use plugin memory and removable drives. In particular, business keyboards also tend to be more durable. Overall construction is also likely to be better, with heavier gauge case material, hinges, and fasteners intended to stand up better to the rigor of travel.

All this can make a difference down the road if you develop a need for more memory or a bigger main drive.

As far as the operating system, my general rule is that if you have to ask, the Home version of Windows will probably work fine for you. There is real, value added incremental functionality in the Professional version. Much of it is related to networking support, but there are other differences as well.

As far as usability, compatibility, and performance, you shouldn't see a difference.

Here how one source describes the difference between Win Home and Win Pro:

Windows Home is the basic version of the operating system designed for home users, while Windows Pro is a more advanced version aimed at businesses and professional users. Here are some of the key differences between the two:

Security: Windows Pro includes additional security features such as BitLocker encryption, Windows Defender Application Guard, and Windows Information Protection.

Remote Desktop: Only Windows Pro allows users to connect to a remote computer using Remote Desktop.

Virtualization: Windows Pro includes Hyper-V, a virtualization platform that allows users to create and run virtual machines.

Networking: Windows Pro has additional networking features such as Domain Join, Group Policy Management, and Remote Desktop Services.

Device management: Windows Pro allows for more control over device management, including the ability to manage updates, configure policies, and control access to apps and data.

Overall, Windows Pro includes more features and functionality designed for businesses and professional users, while Windows Home is a more basic version designed for home users.

My new computer came with Win Pro and I haven't seen any differences in what use I make of the computer.