billnikon Loc: Pennsylvania/Ohio/Florida/Maui/Oregon/Vermont

Full frame is the way to go, no cropping necessary. Get as close as you want with the macro lens.

martinfisherphoto Loc: Lake Placid Florida

When using a FF 24MP D600 and a DX 24MP D7200 I choose the D600 for the final images. The full frame gave a bit more cleaner resolution. I usually shoot at 2:1 so I fill the frame with both cameras. There is no issue with ISO as with flash you shoot between ISO 200 and lower. That said, it's all about technic, especially flash diffusion. If your pictures are just OK with a DX camera they will Not improve with a FF camera..........

rmalarz Loc: Tempe, Arizona

or your sister.
--Bob

SteveG Loc: Norh Carolina

OH God, anyone but her in the conversation! Lol! What a..............!

berchman Loc: South Central PA

I had a very hot cousin.

SteveG Loc: Norh Carolina

I had one, but it's still your cousin

SteveG Loc: Norh Carolina

I have had both and I prefer full frame with all my shots. I just get that little extra all around in image quality from my full frame. As long as you have the right focal length to start, or move in to your subject more if need be, then full frame gives me a little nicer results.

will47 Loc: Indianapolis, IN

It's all relative.

Cheetah34 Loc: Virginia Beach

A better analogy is "taking a shower with your sister "

camerapapi Loc: Miami, Fl.

In my experience a macro lens because of the "digital factor" will have a longer working distance with a cropped body. I have nothing against that.

Canisdirus

Canon 90D is the clear winner in this race.

If you crop the 6DMII to aspc image size ... you end up with a 10mp image (about).
You retain the 32MP from the 90D with the same FOV.

Cropping FF images can be as good, but you'll need to start with a much higher MP sensor than the 6D's 26 MP sensor.

sippyjug104 Loc: Missouri

I shoot macro and micro focus stacking sessions nearly every day. I believe it is far more about the lens and magnification technique than it is about the sensor of the camera. I adjust the combination of lens, extension tubes, helicoid, or bellows that I use to fill the frame with the subject. Lighting and how to diffuse it softly is very important to creating a pleasing image. I shoot with my lenses (and combination of lenses in series) mounted in reverse so when shooting at higher magnifications the 'apparent f/stop' is based on what the subject sees which is different than what the camera lens f/stop dial is set at. For example when I use my 28mm lens coupled to a reverse mounted magnifying lens mounted on 68mm of extension tubes to achieve an 8-power magnification my f/5.6 setting produces an apparent f/64 which is again why lighting plays an important part for increasing ISO creates very noisy images.

When I'm in the field shooting macro to me it's about the distance from the subject and having enough distance to get the off-camera flash close enough yet not to frighten the subject although I've yet to scare away a wildflower.

When it comes to cropping an image, pixels in the area of non-interest are 'thrown away' and what remains is resized so to those who may crop their images in post, a full frame sensor would be a better choice to avoid pixelation and digital noise.

Of course processing the images for print is much different than to display on-screen or to share via the internet.

Retired CPO Loc: Travel full time in an RV

And you apparently have never experienced the benefits of dating a raring to go distant cousin.

berchman Loc: South Central PA

What if your sister is Christina Hendricks?

Retired CPO Loc: Travel full time in an RV

And I think we are ALL forgetting, again, that in film days everybody and his brother was using a "full frame" camera. It was called a 35mm. I had to go to medium format film to get out of every one's path.