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A New Type Of COVID-19 Vaccine Could Debut Soon
Nov 1, 2021 13:42:54   #
Rose42
 
Interesting.

A new kind of COVID-19 vaccine could be available as soon as this summer.

It's what's known as a protein subunit vaccine. It works somewhat differently from the current crop of vaccines authorized for use in the U.S. but is based on a well-understood technology and doesn't require special refrigeration.

The rest of the article

https://www.npr.org/sections/health-shots/2021/06/06/1003328413/new-type-of-covid-vaccine-could-debut-soon

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Nov 1, 2021 15:10:21   #
David Martin Loc: Cary, NC
 
Rose42 wrote:
Interesting.

A new kind of COVID-19 vaccine could be available as soon as this summer.

It's what's known as a protein subunit vaccine. It works somewhat differently from the current crop of vaccines authorized for use in the U.S. but is based on a well-understood technology and doesn't require special refrigeration.

The rest of the article

https://www.npr.org/sections/health-shots/2021/06/06/1003328413/new-type-of-covid-vaccine-could-debut-soon

Novavax has never produced a vaccine until now. Nevertheless, they received a grant of $1.6 billion from the U.S. to produce a Covid-19 vaccine. The company has had numerous setbacks in development and production, including:

- purity issues (FDA requires a minimum of 90% purity for each batch of vaccine, but Novavax has reportedly been closer to 70%). Low purity levels may indicate the presence of contaminants or other unnecessary substances in the final product which could reduce effectiveness of the vaccine and/or cause more side effects.
- the methods Novavax has used to test their vaccine's effectiveness have fallen short of FDA standards.

Production of vaccine has been markedly slowed and numerous batches have had to be discarded.
Many published reports suggest that the Novavax vaccine is primarily intended to be sent to third world countries.
Novavax received its first emergency use authorization today, from Indonesia.

https://www.politico.com/news/2021/10/19/novavax-vaccine-rush-process-global-campaign-516298
https://news.yahoo.com/novavax-tumbles-politico-report-covid-133047336.html

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Nov 1, 2021 16:00:20   #
Rose42
 
David Martin wrote:
Novavax has never produced a vaccine until now. Nevertheless, they received a grant of $1.6 billion from the U.S. to produce a Covid-19 vaccine. The company has had numerous setbacks in development and production, including:

- purity issues (FDA requires a minimum of 90% purity for each batch of vaccine, but Novavax has reportedly been closer to 70%). Low purity levels may indicate the presence of contaminants or other unnecessary substances in the final product which could reduce effectiveness of the vaccine and/or cause more side effects.
- the methods Novavax has used to test their vaccine's effectiveness have fallen short of FDA standards.

Production of vaccine has been markedly slowed and numerous batches have had to be discarded.
Many published reports suggest that the Novavax vaccine is primarily intended to be sent to third world countries.
Novavax received its first emergency use authorization today, from Indonesia.

https://www.politico.com/news/2021/10/19/novavax-vaccine-rush-process-global-campaign-516298
https://news.yahoo.com/novavax-tumbles-politico-report-covid-133047336.html
Novavax has never produced a vaccine until now. Ne... (show quote)


There was another one mentioned as well - Medicago whose vaccine is plant based

Reply
 
 
Nov 1, 2021 17:49:36   #
David Martin Loc: Cary, NC
 
Rose42 wrote:
There was another one mentioned as well - Medicago whose vaccine is plant based

Yes, and it's interesting.
Medicago (a Japanese pharma company) uses a plant that is "related to the tobacco plant" to make the protein particle that triggers the immune response.
Curious they did not say "tobacco plant", but rather a plant "related" to the tobacco plant.
Because Medicago is owned by Phillip-Morris (something your NPR article didn't mention) -- coincidence???

Reply
Nov 1, 2021 18:56:57   #
Rose42
 
David Martin wrote:
Yes, and it's interesting.
Medicago (a Japanese pharma company) uses a plant that is "related to the tobacco plant" to make the protein particle that triggers the immune response.
Curious they did not say "tobacco plant", but rather a plant "related" to the tobacco plant.
Because Medicago is owned by Phillip-Morris (something your NPR article didn't mention) -- coincidence???


Maybe. Thats what I find most interesting

A drugmaker backed by the company that owns Marlboro cigarettes plans to launch the world's first plant-based COVID-19 vaccine

https://www.businessinsider.com/covid-vaccine-plant-based-marlboro-mitsubishi-tanabe-pharma-medicago-2021-10?op=1

Reply
Nov 2, 2021 08:04:23   #
Bob Smith Loc: Banjarmasin
 
Rose42 wrote:
Maybe. Thats what I find most interesting

A drugmaker backed by the company that owns Marlboro cigarettes plans to launch the world's first plant-based COVID-19 vaccine

https://www.businessinsider.com/covid-vaccine-plant-based-marlboro-mitsubishi-tanabe-pharma-medicago-2021-10?op=1


Apparently to take the vaccine you have to soak tobacco with it, then with very thin paper roll the tobacco into a tube and place the tube in your mouth, then set fire to the other end and inhale the vaccine soaked smoke. Quite an innovation.

Reply
Nov 2, 2021 08:27:26   #
thom w Loc: San Jose, CA
 
David Martin wrote:
Yes, and it's interesting.
Medicago (a Japanese pharma company) uses a plant that is "related to the tobacco plant" to make the protein particle that triggers the immune response.
Curious they did not say "tobacco plant", but rather a plant "related" to the tobacco plant.
Because Medicago is owned by Phillip-Morris (something your NPR article didn't mention) -- coincidence???


Since there are currently viable vaccines available, including one that is fully approved, I wonder if it might be harder to get emergency approval for new ones. Obviously the emergency is not the same as it was. It would make sense to me, but I don't really have a position. I'm mostly just curious.

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Nov 2, 2021 08:43:49   #
Rose42
 
Bob Smith wrote:
Apparently to take the vaccine you have to soak tobacco with it, then with very thin paper roll the tobacco into a tube and place the tube in your mouth, then set fire to the other end and inhale the vaccine soaked smoke. Quite an innovation.



Reply
Nov 2, 2021 09:09:05   #
David Martin Loc: Cary, NC
 
thom w wrote:
Since there are currently viable vaccines available, including one that is fully approved, I wonder if it might be harder to get emergency approval for new ones. Obviously the emergency is not the same as it was. It would make sense to me, but I don't really have a position. I'm mostly just curious.

The protein subunit vaccines have the advantage of being stored at room temperature. Even though the U.S. is largely footing the bill, the vaccines will be used primarily in areas of the world that lack the technology to refrigerate the mRNA vaccines.

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Nov 2, 2021 09:09:30   #
David Martin Loc: Cary, NC
 
Bob Smith wrote:
Apparently to take the vaccine you have to soak tobacco with it, then with very thin paper roll the tobacco into a tube and place the tube in your mouth, then set fire to the other end and inhale the vaccine soaked smoke. Quite an innovation.

And what have you been smoking?

Reply
Nov 2, 2021 10:41:20   #
Fotoartist Loc: Detroit, Michigan
 
Bob Smith wrote:
Apparently to take the vaccine you have to soak tobacco with it, then with very thin paper roll the tobacco into a tube and place the tube in your mouth, then set fire to the other end and inhale the vaccine soaked smoke. Quite an innovation.


I don't know about the tobacco ingredient.

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Nov 2, 2021 13:41:16   #
redlegfrog
 
Bob Smith wrote:
Apparently to take the vaccine you have to soak tobacco with it, then with very thin paper roll the tobacco into a tube and place the tube in your mouth, then set fire to the other end and inhale the vaccine soaked smoke. Quite an innovation.


I wasn't planning to start smoking again until I reached 75 years of age but you put up a good argument to start a little sooner!

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Nov 2, 2021 15:40:19   #
Bob Smith Loc: Banjarmasin
 

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