MIT & Harvard Study Suggests mRNA Vaccine Might Permanently Alter DNA After All: Please don’t just flap your gums. Find scientific arguments to refute. Looks interesting...

soba1 Loc: Somewhere In So Ca

Please don’t just flap your gums. Find scientific arguments to refute.
Looks interesting

https://anti-empire.com/mit-harvard-study-sheds-light-on-whether-mrna-vaccine-might-permanently-alter-dna-after-all/

letmedance Loc: Walnut, Ca.

Monsanto spliced a gene in corn to make it resistant to it’s Roundup product. I guess we will be resistant the Covid virus and pass it to our offspring. 😄😏😏😏

soba1 Loc: Somewhere In So Ca

letmedance wrote:

Monsanto spliced a gene in corn to make it resistant to it’s Roundup product. I guess we will be resistant the Covid virus and pass it to our offspring. 😄😏😏😏

Lol

dpullum Loc: Tampa Florida

My understanding of our DNA is that it is mostly "junk DNA" ... "Much of our genome has no apparent purpose. Is it so-called “junk DNA” or do we simply not understand it?" My personal observation in life is that some people are more trashy than others... some downright junk.
https://www.discovermagazine.com/health/our-cells-are-filled-with-junk-dna-heres-why-we-need-it

soba1 Loc: Somewhere In So Ca

dpullum wrote:

My understanding of our DNA is that it is mostly "junk DNA" ... "Much of our genome has no apparent purpose. Is it so-called “junk DNA” or do we simply not understand it?" My personal observation in life is that some people are more trashy than others... some downright junk.
https://www.discovermagazine.com/health/our-cells-are-filled-with-junk-dna-heres-why-we-need-it

But there is a possibility that RNA can have serious consequences mixing mixing with our DNA

WNYShooter Loc: WNY

soba1 wrote:

But there is a possibility that RNA can have serious consequences mixing mixing with our DNA

Absolutely! Fact is there is very little clinical or testing history on all of the Covid vaccines.

Thalidomide was once touted as a safe medicine, and it wasn't even until sometime after 2010 that science finally figured out what it actually did to cause all of the birth defects attributed to it.

berchman Loc: South Central PA

soba1 wrote:

Please don’t just flap your gums. Find scientific arguments to refute.
Looks interesting

https://anti-empire.com/mit-harvard-study-sheds-light-on-whether-mrna-vaccine-might-permanently-alter-dna-after-all/

I saw the words “could” and “ conjecture.”
Could I be transformed into a virus? Maybe I’m already a virus.

John_F Loc: Minneapolis, MN

Quite a few years ago I read a book entitled Genome, so my memory is not perfect. One point made was that dna structures were superseded but not eliminated. So those structures called “junk” are not junk but just superceded

Fotoartist Loc: Detroit, Michigan

dpullum wrote:

My understanding of our DNA is that it is mostly "junk DNA" ... "Much of our genome has no apparent purpose. Is it so-called “junk DNA” or do we simply not understand it?" My personal observation in life is that some people are more trashy than others... some downright junk.
https://www.discovermagazine.com/health/our-cells-are-filled-with-junk-dna-heres-why-we-need-it

Like Democrats and Leftists I presume.

berchman Loc: South Central PA

Fotoartist wrote:

Like Democrats and Leftists I presume.

Clever.

soba1 Loc: Somewhere In So Ca

WNYShooter wrote:

Absolutely! Fact is there is very little clinical or testing history on all of the Covid vaccines.

Thalidomide was once touted as a safe medicine, and it wasn't even until sometime after 2010 that science finally figured out what it actually did to cause all of the birth defects attributed to it.

soba1 Loc: Somewhere In So Ca

John_F wrote:

Quite a few years ago I read a book entitled Genome, so my memory is not perfect. One point made was that dna structures were superseded but not eliminated. So those structures called “junk” are not junk but just superceded

DukeTarHeel Loc: NC's "Research Triangle"

soba1 wrote:

Please don’t just flap your gums. Find scientific arguments to refute.
Looks interesting

https://anti-empire.com/mit-harvard-study-sheds-light-on-whether-mrna-vaccine-might-permanently-alter-dna-after-all/

Soba - my daughter is an immunologist who graduated from the Duke School of Medicine. I asked her to review and comment. I thought I'd share it.

The paper they cited was a preprint that came out last year and was about the virus itself, not the vaccines: https://www.biorxiv.org/content/10.1101/2020.12.12.422516v1

It looks like it hasn't been published yet (meaning still under peer review.)

Furthermore, aside from the data where they looked at primary cells taken from people who had been infected, I think a lot of the data isn't that compelling. It's certainly interesting that they seem to have found cells from patients that have Covid sequences integrated into the genom, but that doesn't tell us mechanism of action.

They did a whole bunch of their LINE-1 induction experiments in culture, and cultured cells are known to be more vulnerable to retrotransposons and to infection from retroviruses. Infamously, back in 2010 everyone thought a virus called XMRV was sweeping across the country and causing chronic fatigue syndrome as well as prostate cancer. This was based on some sequencing of samples from patients, and some experiments where they successfully infected some very permissive cell lines. Then, when someone tried to infect human primary cells, or even cell lines that had normal expression of viral restriction factors, the whole thing fell apart because XMRV turned out to just be a lab contaminant from mice that couldn't infect real human cells.

The part of the paper dealing with increased expression of LINE-1 during an experiment meant to emulate a cytokine storm is not really comparable to how most people experience Covid or even vaccination. Most people do not develop severe Covid, so arguably it's the immune dysregulation that is contributing to LINE-1 upregulation and not any of Covid's features itself. It would be interesting to see how this compares with other viruses that are capable of causing this amount of immune dysregulation, such as ebolaviruses.

Furthermore, a good vaccine is not designed to provoke immune dysregulation, since in a cytokine storm all cytokines are being expressed at the same time, basically all shouting over each other. It would be like if one person shouted "fire" in a theater and 2 others started shouting for her to shut up, and then 5 more started shouting out their favorite movie lines in response... not exactly helping the situation if there is a fire. A systemic inflammatory response also disrupts hemostasis- clotting factors get used up so fast that blood vessels become leaky. The difference between life and death in patients with ebolavirus was whether cytokine expression became deregulated... so that would be exactly the kind of outcome that vaccine design would want to avoid. You don't train people's immune systems to react to something the complete wrong way!

Finally, there's the fact that this blog has an agenda. U.S. pharma has been objecting to the Sputnik V vaccine for months, whereas the Russian government has been objecting to the Pfizer and Moderna vaccines for months. They're both being ridiculous. Sputnik V works fine, Pfizer works fine, Moderna works fine. Vaccine nationalism is going to screw everyone if it means vaccination rates never get high enough to slow the evolution of covid. If we end up with a bunch more variants that are capable of immune evasion because we never managed to get global hard immunity, we are all going to be sorry because the economy everywhere is going to take a hit, as will social stability. Pfizer is already talking about raising the price of their vaccine, which is insane. That's like putting a toll booth on every road. At a certain point it becomes counterproductive.

Anyways, this blog isn't interested in actually exploring the science, it's interested in speculation for a cause, and that sucks. I see it accepts donations from all different currencies and from crypto... not really a great sign. I have a healthy mistrust of all mainstream news outlets but that doesn't mean it's good to fall into the arms of scam artists that prey on disillusionment. TL;DR the folks hanging out on the message board you check out are snorting lines of confirmation bias and it shows.

Rose42

DukeTarHeel wrote:

Soba - my daughter is an immunologist who graduated from the Duke School of Medicine. I asked her to review and comment. I thought I'd share it.

The paper they cited was a preprint that came out last year and was about the virus itself, not the vaccines: https://www.biorxiv.org/content/10.1101/2020.12.12.422516v1

It looks like it hasn't been published yet (meaning still under peer review.)

Furthermore, aside from the data where they looked at primary cells taken from people who had been infected, I think a lot of the data isn't that compelling. It's certainly interesting that they seem to have found cells from patients that have Covid sequences integrated into the genom, but that doesn't tell us mechanism of action.

They did a whole bunch of their LINE-1 induction experiments in culture, and cultured cells are known to be more vulnerable to retrotransposons and to infection from retroviruses. Infamously, back in 2010 everyone thought a virus called XMRV was sweeping across the country and causing chronic fatigue syndrome as well as prostate cancer. This was based on some sequencing of samples from patients, and some experiments where they successfully infected some very permissive cell lines. Then, when someone tried to infect human primary cells, or even cell lines that had normal expression of viral restriction factors, the whole thing fell apart because XMRV turned out to just be a lab contaminant from mice that couldn't infect real human cells.

The part of the paper dealing with increased expression of LINE-1 during an experiment meant to emulate a cytokine storm is not really comparable to how most people experience Covid or even vaccination. Most people do not develop severe Covid, so arguably it's the immune dysregulation that is contributing to LINE-1 upregulation and not any of Covid's features itself. It would be interesting to see how this compares with other viruses that are capable of causing this amount of immune dysregulation, such as ebolaviruses.

Furthermore, a good vaccine is not designed to provoke immune dysregulation, since in a cytokine storm all cytokines are being expressed at the same time, basically all shouting over each other. It would be like if one person shouted "fire" in a theater and 2 others started shouting for her to shut up, and then 5 more started shouting out their favorite movie lines in response... not exactly helping the situation if there is a fire. A systemic inflammatory response also disrupts hemostasis- clotting factors get used up so fast that blood vessels become leaky. The difference between life and death in patients with ebolavirus was whether cytokine expression became deregulated... so that would be exactly the kind of outcome that vaccine design would want to avoid. You don't train people's immune systems to react to something the complete wrong way!

Finally, there's the fact that this blog has an agenda. U.S. pharma has been objecting to the Sputnik V vaccine for months, whereas the Russian government has been objecting to the Pfizer and Moderna vaccines for months. They're both being ridiculous. Sputnik V works fine, Pfizer works fine, Moderna works fine. Vaccine nationalism is going to screw everyone if it means vaccination rates never get high enough to slow the evolution of covid. If we end up with a bunch more variants that are capable of immune evasion because we never managed to get global hard immunity, we are all going to be sorry because the economy everywhere is going to take a hit, as will social stability. Pfizer is already talking about raising the price of their vaccine, which is insane. That's like putting a toll booth on every road. At a certain point it becomes counterproductive.

Anyways, this blog isn't interested in actually exploring the science, it's interested in speculation for a cause, and that sucks. I see it accepts donations from all different currencies and from crypto... not really a great sign. I have a healthy mistrust of all mainstream news outlets but that doesn't mean it's good to fall into the arms of scam artists that prey on disillusionment. TL;DR the folks hanging out on the message board you check out are snorting lines of confirmation bias and it shows.

Soba - my daughter is an immunologist who graduate... (show quote)

That blog has an agenda? Surprise!

Interesting post. Thanks.

soba1 Loc: Somewhere In So Ca

DukeTarHeel wrote:

Soba - my daughter is an immunologist who graduated from the Duke School of Medicine. I asked her to review and comment. I thought I'd share it.

The paper they cited was a preprint that came out last year and was about the virus itself, not the vaccines: https://www.biorxiv.org/content/10.1101/2020.12.12.422516v1

It looks like it hasn't been published yet (meaning still under peer review.)

Furthermore, aside from the data where they looked at primary cells taken from people who had been infected, I think a lot of the data isn't that compelling. It's certainly interesting that they seem to have found cells from patients that have Covid sequences integrated into the genom, but that doesn't tell us mechanism of action.

They did a whole bunch of their LINE-1 induction experiments in culture, and cultured cells are known to be more vulnerable to retrotransposons and to infection from retroviruses. Infamously, back in 2010 everyone thought a virus called XMRV was sweeping across the country and causing chronic fatigue syndrome as well as prostate cancer. This was based on some sequencing of samples from patients, and some experiments where they successfully infected some very permissive cell lines. Then, when someone tried to infect human primary cells, or even cell lines that had normal expression of viral restriction factors, the whole thing fell apart because XMRV turned out to just be a lab contaminant from mice that couldn't infect real human cells.

The part of the paper dealing with increased expression of LINE-1 during an experiment meant to emulate a cytokine storm is not really comparable to how most people experience Covid or even vaccination. Most people do not develop severe Covid, so arguably it's the immune dysregulation that is contributing to LINE-1 upregulation and not any of Covid's features itself. It would be interesting to see how this compares with other viruses that are capable of causing this amount of immune dysregulation, such as ebolaviruses.

Furthermore, a good vaccine is not designed to provoke immune dysregulation, since in a cytokine storm all cytokines are being expressed at the same time, basically all shouting over each other. It would be like if one person shouted "fire" in a theater and 2 others started shouting for her to shut up, and then 5 more started shouting out their favorite movie lines in response... not exactly helping the situation if there is a fire. A systemic inflammatory response also disrupts hemostasis- clotting factors get used up so fast that blood vessels become leaky. The difference between life and death in patients with ebolavirus was whether cytokine expression became deregulated... so that would be exactly the kind of outcome that vaccine design would want to avoid. You don't train people's immune systems to react to something the complete wrong way!

Finally, there's the fact that this blog has an agenda. U.S. pharma has been objecting to the Sputnik V vaccine for months, whereas the Russian government has been objecting to the Pfizer and Moderna vaccines for months. They're both being ridiculous. Sputnik V works fine, Pfizer works fine, Moderna works fine. Vaccine nationalism is going to screw everyone if it means vaccination rates never get high enough to slow the evolution of covid. If we end up with a bunch more variants that are capable of immune evasion because we never managed to get global hard immunity, we are all going to be sorry because the economy everywhere is going to take a hit, as will social stability. Pfizer is already talking about raising the price of their vaccine, which is insane. That's like putting a toll booth on every road. At a certain point it becomes counterproductive.

Anyways, this blog isn't interested in actually exploring the science, it's interested in speculation for a cause, and that sucks. I see it accepts donations from all different currencies and from crypto... not really a great sign. I have a healthy mistrust of all mainstream news outlets but that doesn't mean it's good to fall into the arms of scam artists that prey on disillusionment. TL;DR the folks hanging out on the message board you check out are snorting lines of confirmation bias and it shows.

Soba - my daughter is an immunologist who graduate... (show quote)

Duke thanks, and tell your daughter thanks as well greatly appreciated.
I’m still going to hold out for a bit and see how others are doing who have taken
the Vax. If I do decide to I won’t be as worried.