F.F. Drive-in's are relatively safe, but have a mask on and rubber gloves close-by. If possible stay in a highly $$$ rated hotel, NOT a small cheap Motel. Possibly even a well recommended B&B, if groceries are needed find store you can "Call-in" your "Must have" order then they bring it out and put it in your car, (Walmarts, Kroger, etc.) Try not to use Gas Station Rest Rooms, if necessary bring wipes with you. Be Smart & Be Safe!! Also wear Gloves when Pumping gas, a million strangers have come before you!! Also, do not Swim in Hotel Pool.

While I am sure it can be done safely however, I would consider staying home and making day trips. The kind where you stay in your own vehicle, get out where it is safe and take photos, use drive through access for food and come back home at the end of the day. I think it is playing the odds. Stop to think of the number of surfaces you would need to touch going into hotels etc. and in the hotel room, someone may have touched many of the surfaces and a little thing like turning on the TV could cause you to pick up something you want to avoid. I find day trips fun and enjoy the ability to relax at home in the evening.

In late April, my wife and I traveled home to NY from FL. I researched all the travel tips I could find and we came up with a final plan of attack.
First of all, stay in a major hotel chain. Someone said that a major chain would more likely sanitize their rooms better because they’re more anxious to keep your business. We stayed at a Marriott off the beaten path.
Wear gloves and a mask.
Before we entered the room we wiped down the doorknob with sanitary wipes.
Inside the room we wiped down all surfaces that we would put our possessions on (luggage, etc.) and all countertops that we might touch or put stuff on.

Pull the coverlet/quilt and throw it in a corner. ChamberMaids are less likely to wash or replace them if they “appear to be clean.”
We sprayed the cover sheet with sanitizer, pulled it away from the fitted sheet, and sprayed the other surfaces of the sheets.
Bring zip lock bags for the TV remotes. That’s the dirtiest item in the room.
Make sure you wipe every surface in any area like night stands and the bathroom sink countertops, toilet bowl and seat, faucets. I know I mentioned this but it’s important.
Don’t eat in the dining room if you can avoid it.
The hotel provided a bag of breakfast foods on our way out for each of us.
On the trip we brought our own drinks and food (peanut butter & snacks) to make in the car for the ride.
Your own towels probably wouldn’t be a bad idea.
End note...we’re alive & no COVID-19 as a result.
Wear gloves and masks in rest areas and carry some sanitary wipes in zip locks for the restrooms.