Older flash can have trigger voltage as high as 600 volts! That wasn't a problem back in the days of cameras that were predominantly mechanical. But in the late 1970s and early 1980s cameras started seeing electronics used internally, at first just to control shutter speeds and for metering... but gradually increasing to perform more and more functions.
This became a severe problem as cameras became more electronic... eventually becoming the little computers to capture images we use today! For example, some of the later Canon film cameras and early DSLRs can only tolerate 6 volts. An old 283 with 600V will fry those cameras' circuitry after just a few pops! Other flashes with far less extreme trigger might only do damage over time, with repeated use.
Here is a partial list of flashes and user-measured trigger voltages:
http://www.botzilla.com/photo/strobeVolts.htmlHere's further description of the problem and how to measure it yourself using an inexpensive, digital Voltage Ohm Meter (VOM, available at Lowes, Home Depot, etc.):
http://dpanswers.com/content/genrc_flash_measuretv.phpAround 2004 the International Standards Organization recommended all camera makers insulate their cameras to tolerate trigger voltage of 24V minimum. Both Canon and Nikon far exceeded that by each upgrading their cameras to tolerate 250V. The list of cameras in an earlier response appears to be correct.... basically Canon 10D (2003), 300D (aka Digital Rebel, 2003) and earlier models have a 6V trigger voltage limit. Every Canon DSLR from the 20D (2004) and 350D (aka Rebel XT, 2005) onward is able to handle up to 250V trigger voltage.
The PC sync socket, if the camera has one, has the same trigger voltage tolerance as the hot shoe. (Note: A "PC" socket is a connection normally used for wired triggering a studio strobe system. In this case, "PC" stands for "Prontor-Compur", the manufacturers who first established this standardized type of connector in the 1950s. It does NOT stand for "personal computer" or "politically correct"
, in this particular context. For example, a camera's PC socket has no relation at all with a mini-USB socket allowing the camera to be tethered to a personal computer.)
This was Canon USA's Tech Guru Chuck Westfall's statement on the subject in 2007:
"The trigger circuit voltage (TCV) rating for any EOS SLR is the same on the hot shoe as it is on the PC terminal (if the camera has one), but the acceptable TCV level varies according to the camera model. Incidentally, the main reason for the difference is the way the X-sync signal is generated. With the 250V cameras, the X-sync signal is generated electronically. With the 6V cameras, the X-sync signal is generated mechanically. There are no guarantees, but going forward I anticipate that most if not all future EOS SLRs will be safe for TCV up to 250 volts."A Wein "Safe Sync" is one way to isolate a flash with a high trigger voltage to prevent damage to a camera that can't tolerate it. There are other brands, but any of them will need to be tested. As one response notes, they don't work with all flashes and strobes!
Yes, it's also possible to use an optical slave trigger, such as those shown in earlier posts. The problem with an optical trigger is that anybody else's flash going off nearby will trigger your flash too. They also may not work with all flashes/strobes and might have limited working distance in some lighting conditions.
A wireless transmitter/receiver arrangement is another way to protect your camera from high flash/strobe trigger voltages. HOWEVER, if you go this route you should check that the wireless receiver that will be attached to the flash can handle the voltage. For example, PocketWizard Plus II have a 100V limit, while PocketWizard Plus III have been beefed up to handle as high as 300V without damage.