A New Type Of C****-** V*****e Could Debut Soon: Interesting. A new kind of C****-** v*****e could be available as soon as this summer. It's what's known as a protein subunit v*****e.

Rose42

Interesting.

A new kind of C****-** v*****e could be available as soon as this summer.

It's what's known as a protein subunit v*****e. It works somewhat differently from the current crop of v*****es authorized for use in the U.S. but is based on a well-understood technology and doesn't require special refrigeration.

The rest of the article

https://www.npr.org/sections/health-shots/2021/06/06/1003328413/new-type-of-c***d-v*****e-could-debut-soon

David Martin Loc: Cary, NC

Rose42 wrote:

Interesting.

A new kind of C****-** v*****e could be available as soon as this summer.

It's what's known as a protein subunit v*****e. It works somewhat differently from the current crop of v*****es authorized for use in the U.S. but is based on a well-understood technology and doesn't require special refrigeration.

The rest of the article

https://www.npr.org/sections/health-shots/2021/06/06/1003328413/new-type-of-c***d-v*****e-could-debut-soon

Novavax has never produced a v*****e until now. Nevertheless, they received a grant of $1.6 billion from the U.S. to produce a C****-** v*****e. The company has had numerous setbacks in development and production, including:

- purity issues (FDA requires a minimum of 90% purity for each batch of v*****e, but Novavax has reportedly been closer to 70%). Low purity levels may indicate the presence of contaminants or other unnecessary substances in the final product which could reduce effectiveness of the v*****e and/or cause more side effects.
- the methods Novavax has used to test their v*****e's effectiveness have fallen short of FDA standards.

Production of v*****e has been markedly slowed and numerous batches have had to be discarded.
Many published reports suggest that the Novavax v*****e is primarily intended to be sent to third world countries.
Novavax received its first e*******y use a***********n today, from Indonesia.

https://www.politico.com/news/2021/10/19/novavax-v*****e-rush-process-global-campaign-516298
https://news.yahoo.com/novavax-tumbles-politico-report-c***d-133047336.html

Rose42

David Martin wrote:

Novavax has never produced a v*****e until now. Ne... (show quote)

There was another one mentioned as well - Medicago whose v*****e is plant based

David Martin Loc: Cary, NC

Rose42 wrote:

There was another one mentioned as well - Medicago whose v*****e is plant based

Yes, and it's interesting.
Medicago (a Japanese pharma company) uses a plant that is "related to the tobacco plant" to make the protein particle that triggers the immune response.
Curious they did not say "tobacco plant", but rather a plant "related" to the tobacco plant.
Because Medicago is owned by Phillip-Morris (something your NPR article didn't mention) -- coincidence???

Rose42

David Martin wrote:

Yes, and it's interesting.
Medicago (a Japanese pharma company) uses a plant that is "related to the tobacco plant" to make the protein particle that triggers the immune response.
Curious they did not say "tobacco plant", but rather a plant "related" to the tobacco plant.
Because Medicago is owned by Phillip-Morris (something your NPR article didn't mention) -- coincidence???

Maybe. Thats what I find most interesting

A drugmaker backed by the company that owns Marlboro cigarettes plans to launch the world's first plant-based C****-** v*****e

https://www.businessinsider.com/c***d-v*****e-plant-based-marlboro-mitsubishi-tanabe-pharma-medicago-2021-10?op=1

Bob Smith Loc: Banjarmasin

Rose42 wrote:

Maybe. Thats what I find most interesting

A drugmaker backed by the company that owns Marlboro cigarettes plans to launch the world's first plant-based C****-** v*****e

https://www.businessinsider.com/c***d-v*****e-plant-based-marlboro-mitsubishi-tanabe-pharma-medicago-2021-10?op=1

Apparently to take the v*****e you have to soak tobacco with it, then with very thin paper roll the tobacco into a tube and place the tube in your mouth, then set fire to the other end and inhale the v*****e soaked smoke. Quite an innovation.

thom w Loc: San Jose, CA

David Martin wrote:

Yes, and it's interesting.
Medicago (a Japanese pharma company) uses a plant that is "related to the tobacco plant" to make the protein particle that triggers the immune response.
Curious they did not say "tobacco plant", but rather a plant "related" to the tobacco plant.
Because Medicago is owned by Phillip-Morris (something your NPR article didn't mention) -- coincidence???

Since there are currently viable v*****es available, including one that is fully approved, I wonder if it might be harder to get emergency approval for new ones. Obviously the emergency is not the same as it was. It would make sense to me, but I don't really have a position. I'm mostly just curious.

Rose42

Bob Smith wrote:

Apparently to take the v*****e you have to soak tobacco with it, then with very thin paper roll the tobacco into a tube and place the tube in your mouth, then set fire to the other end and inhale the v*****e soaked smoke. Quite an innovation.

David Martin Loc: Cary, NC

thom w wrote:

Since there are currently viable v*****es available, including one that is fully approved, I wonder if it might be harder to get emergency approval for new ones. Obviously the emergency is not the same as it was. It would make sense to me, but I don't really have a position. I'm mostly just curious.

The protein subunit v*****es have the advantage of being stored at room temperature. Even though the U.S. is largely footing the bill, the v*****es will be used primarily in areas of the world that lack the technology to refrigerate the m**A v*****es.

David Martin Loc: Cary, NC

Bob Smith wrote:

Apparently to take the v*****e you have to soak tobacco with it, then with very thin paper roll the tobacco into a tube and place the tube in your mouth, then set fire to the other end and inhale the v*****e soaked smoke. Quite an innovation.

And what have you been smoking?

Fotoartist Loc: Detroit, Michigan

Bob Smith wrote:

Apparently to take the v*****e you have to soak tobacco with it, then with very thin paper roll the tobacco into a tube and place the tube in your mouth, then set fire to the other end and inhale the v*****e soaked smoke. Quite an innovation.

I don't know about the tobacco ingredient.

redlegfrog

Bob Smith wrote:

Apparently to take the v*****e you have to soak tobacco with it, then with very thin paper roll the tobacco into a tube and place the tube in your mouth, then set fire to the other end and inhale the v*****e soaked smoke. Quite an innovation.

I wasn't planning to start smoking again until I reached 75 years of age but you put up a good argument to start a little sooner!

Bob Smith Loc: Banjarmasin