Having been on three tours of Europe, I can recommend that you carry one camera with a moderate zoom lens with a range of 24-105mm.
You will need nothing else except accessories, such as a UV filter for the lens (and maybe a circular polarizer), spare battery (with battery charger), one or two spare memory cards, a card reader, a small lens cleaning kit (cleaning fluid, microcloth rag, a brush, and a small blower [optional]), and a right-sized camera bag to hold everything.
If you do flash lighting, then bring a flash unit with a long cord to get the flash unit off the camera. Include a set or two of spare batteries. You may wish to add a flag for the flash unit head to direct the flash lighting for bouncing it off surfaces.
That's about it.
The airlines I've flown have allowed me to carry my camera bag with me on the plane so I can avoid checking it as luggage.
The versatility of a moderate zoom lens will serve you well for the varying conditions and subjects you will encounter.
Others may insist on a fixed focal length lens (a prime lens) for your trip. It will limit you, despite the insistence that you can "zoom with your feet."
Let me please say that I also routinely carry a high-end point-and-shoot camera (Canon G 9X), in a sling pouch, for doing candids and for its perceived unobtrusiveness.
BTW: I presume you will take along a laptop computer to which you will download your images at the end of the day. Note that the airlines I've flown allow me to carry my laptop aboard the plane. Doing so enables me to avoid checking my computer as luggage. A better laptop will also let you work on your photos during your trip.
But if no laptop, then you will want to consider a backup device to which you can download your images. I note that some shooters fill up memory cards for later downloading. This option might (or might not) work for you. I prefer my laptop for downloading and a portable external hard drive for making a backup of my downloaded images.
Enjoy Europe. You will see there many subjects worthy of photographing.
MattG wrote:
Mid April we’re going to visit Italy (First time). We’re planning to stay three days in Rome, three days in Venice and three days in Florence. I have two cameras to choose from for the trip. Nikon D850, And Fuji X 100 F. Fuji would be easier,camera with fixed lens f/2 35 mm equivalent.
For Nikon I have 16-35 f4, 24-70 2.8, 35 1.8, 501.8 and 28-3003.5-5.6.
Any suggestions for a good combination of camera and lenses would be appreciated
Thanks