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Feb 7, 2015 11:52:21   #
NeilL Loc: British-born Canadian
 
larrypayne wrote:
The Haaertz article does not say what you posted.

The gene is not described as a mutation. It's described as a gene which all Ashkenazi Jews possess.

What is your source?



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Feb 7, 2015 12:03:08   #
larrypayne Loc: Texas Hill Country
 
James Shaw wrote:
:thumbup: :thumbup: My grandmother forewarned me about people like Larry. She said there will always be people in the world without any moral scruples, at all.


Your grandmother was pointing out that you lacked moral scruples, James.

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Feb 7, 2015 12:06:02   #
larrypayne Loc: Texas Hill Country
 
Try harder to be coherent, Neil.

It's not that difficult if you have a functioning brain.

Reply
 
 
Feb 7, 2015 12:08:08   #
OldDoc Loc: New York
 
larrypayne wrote:
It appears you have no source for your claims.

It appears I do have a source for my claims - the original paper (Nature Communications 4, Article number: 2739 doi:10.1038/ncomms3739
Received 13 August 2013 Accepted 09 October 2013 Published 19 November 2013). Here is the abstract:

"Schizophrenia and bipolar disorder are major psychiatric disorders with high heritability and overlapping genetic variance. Here we perform a genome-wide association study in an ethnically homogeneous cohort of 904 schizophrenia cases and 1,640 controls drawn from the Ashkenazi Jewish population. We identify a novel genome-wide significant risk locus at chromosome 4q26, demonstrating the potential advantages of this founder population for gene discovery. The top single-nucleotide polymorphism (SNP; rs11098403) demonstrates consistent effects across 11 replication and extension cohorts, totalling 23, 191 samples across multiple ethnicities, regardless of diagnosis (schizophrenia or bipolar disorder), resulting in Pmeta=9.49 × 10&#8722;12 (odds ratio (OR)=1.13, 95% confidence interval (CI): 1.08–1.17) across both disorders and Pmeta=2.67 × 10&#8722;8 (OR=1.15, 95% CI: 1.08–1.21) for schizophrenia alone. In addition, this intergenic SNP significantly predicts postmortem cerebellar gene expression of NDST3, which encodes an enzyme critical to heparan sulphate metabolism. Heparan sulphate binding is critical to neurite outgrowth, axon formation and synaptic processes thought to be aberrant in these disorders."

Quote:
Why would a Jewish news website intentionally mislead readers about the percentage of Ashkenazi Jews who are susceptible to mental disorder?


The Jewish website may not be misleading its readers. I assume that you don't subscribe to "Haaretz", so you (and I, and all non-subscribers) only saw the introductory sentence or two to the article, and then you ran with your instant interpretation. Without going into the complex lingo of genetics (which I have taught at the university level for many years), the authors describe a gene, known as 4q26. A single base mutation of 4q26 is associated with increased risk of developing schizophrenia. They used the Ashkenazi population of schizophrenics because they are relatively homogeneous genetically, but they reported the same mutation to be present across multiple ethnicities, and to be associated with the development of schizophrenia across the board. In point of fact, the purpose of the study was to show how using a genetically homogeneous population can be used to identify specific mutations that affect the general population, but are difficult to link to specific mutations because of their genetic heterogeneity.
If you need any help in understanding any of the Nature Communications paper, I'll be glad to interpret, but the above is a fair summary of their findings.

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Feb 7, 2015 12:09:56   #
James Shaw
 
Quote:
James Shaw wrote:
My grandmother forewarned me about people like Larry. She said there will always be people in the world without any moral scruples, at all.
larrypayne wrote:
Your grandmother was pointing out that you lacked moral scruples, James.


"without any moral scriptures" applies to LarryPayne and to his friend, Hitler, and their ilk. What a way (hatred) to live and end your life.

Reply
Feb 7, 2015 12:18:56   #
NeilL Loc: British-born Canadian
 
larrypayne wrote:
Try harder to be coherent, Neil.

It's not that difficult if you have a functioning brain.



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Feb 7, 2015 12:35:47   #
larrypayne Loc: Texas Hill Country
 
James Shaw wrote:
"without any moral scriptures" applies to LarryPayne and to his friend, Hitler, and their ilk. What a way (hatred) to live and end your life.


Hitler was a friend to Zionists.

Zionists financed Hitler's rise to power.

Hitler killed only progressive Jews.

The ultra right-wing Zionists' escape to Palestine in 1933 was financed by Hitler.

http://www.timesofisrael.com/venezuelan-mp-says-zionists-bush-family-financed-hitler/

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Feb 7, 2015 12:38:45   #
NeilL Loc: British-born Canadian
 
larrypayne wrote:
Hitler was a friend to Zionists.

Zionists financed Hitler's rise to power.

Hitler killed only progressive Jews.

The ultra right-wing Zionists' escape to Palestine in 1933 was financed by Hitler.

http://www.timesofisrael.com/venezuelan-mp-says-zionists-bush-family-financed-hitler/



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Feb 7, 2015 12:56:26   #
larrypayne Loc: Texas Hill Country
 
OldDoc wrote:
The Jewish website may not be misleading its readers. I assume that you don't subscribe to "Haaretz", so you (and I, and all non-subscribers) only saw the introductory sentence or two to the article, and then you ran with your instant interpretation. Without going into the complex lingo of genetics (which I have taught at the university level for many years), the authors describe a gene, known as 4q26. A single base mutation of 4q26 is associated with increased risk of developing schizophrenia. They used the Ashkenazi population of schizophrenics because they are relatively homogeneous genetically, but they reported the same mutation to be present across multiple ethnicities, and to be associated with the development of schizophrenia across the board. In point of fact, the purpose of the study was to show how using a genetically homogeneous population can be used to identify specific mutations that affect the general population, but are difficult to link to specific mutations because of their genetic heterogeneity.
If you need any help in understanding any of the Nature Communications paper, I'll be glad to interpret, but the above is a fair summary of their findings.
The Jewish website may not be misleading its reade... (show quote)


Esoteric medical language can be easily manipulated by a medical professional such as I presume you are.

I read the Haaertz article in it's entirety before they started requiring membership. It did not include any of what you have said.

I have a curiosity about new members who join the Attic forums.

I check out their posting history and I checked yours.

Your introductory post of one of your photos had many complimentary answers and some of them asked questions.

You did not answer any of those friendly replies nor did you answer any of their questions.

I find it a bit odd when a person joins a photography forum and then neglects to answer any of those whose common interest the forum is designed to share.

http://www.uglyhedgehog.com/t-224883-1.html

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Feb 7, 2015 12:58:27   #
larrypayne Loc: Texas Hill Country
 
I have a large audience, Neil.

The largest audience I have on this forum are these:



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Feb 7, 2015 13:07:53   #
James Shaw
 
Quote:
James Shaw wrote:
"without any moral scriptures" applies to LarryPayne and to his friend, Hitler, and their ilk. What a way (hatred) to live and end your life.
larrypayne wrote:
Hitler was a friend to Zionists.

Zionists financed Hitler's rise to power.

Hitler killed only progressive Jews.

The ultra right-wing Zionists' escape to Palestine in 1933 was financed by Hitler.

http://www.timesofisrael.com/venezuelan-mp-says-zionists-bush-family-financed-hitler/


Yeah, sure Larry. Are we now back to that Zionists-thing?

To think Hitler was selective in his killing, you show your dementia once again. Your friend Hitler kill all kinds, Jews, Russians, the demented, and finally your chicken-shit-little Hitler, idol, killed himself, rather than be caught and hung upside down like Mussolini and lady friend.

What a friend, indeed, you have in that maniac.

Reply
 
 
Feb 7, 2015 13:12:02   #
OldDoc Loc: New York
 
larrypayne wrote:
Esoteric medical language can be easily manipulated by a medical professional such as I presume you are.

I read the Haaertz article in it's entirety before they started requiring membership. It did not include any of what you have said.
If you doubt that I portrayed the original paper fairly, why don't you read it yourself, rather than relying on a non-scientist's newspaper interpretation. I have not read the entire Haretz article, but if they said anything beside what I said, then they are wrong. So, instead of ad hominem attacks, how about responding to the facts I put up in the actual research paper?

I have a curiosity about new members who join the Attic forums.

I check out their posting history and I checked yours.

Your introductory post of one of your photos had many complimentary answers and some of them asked questions.

You did not answer any of those friendly replies nor did you answer any of their questions.

I find it a bit odd when a person joins a photography forum and then neglects to answer any of those whose common interest the forum is designed to share.

http://www.uglyhedgehog.com/t-224883-1.html
I did reply, and got into several interesting discussions, one notable one about watches. I have also posted other photographs. If you take a look at the dates, you will find that I joined the Attic well after I began receiving the newsletter, and after I opened an account. In fact, I didn't know the Attic existed until fairly late. I am not a troll, the evidence being that I use reputable sources of information to discredit those who misinterpret or lie, especially about scientific issues. There is lots to do since the cornerstone of ignorance is science denialism.
Esoteric medical language can be easily manipulate... (show quote)

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Feb 7, 2015 13:24:38   #
larrypayne Loc: Texas Hill Country
 
If you had replied to the members, the replies would be recorded for members to see. That is the purpose of a forum--to exchange opinions and ideas.

If you only communicate through PMs, you are defeating the purpose of the forum.

If you're against science denial, what do you think brought down the 3 Towers on 9/11?

Reply
Feb 7, 2015 13:44:14   #
James Shaw
 
larrypayne wrote:
If you had replied to the members, the replies would be recorded for members to see. That is the purpose of a forum--to exchange opinions and ideas.

If you only communicate through PMs, you are defeating the purpose of the forum.

If you're against science denial, what do you think brought down the 3 Towers on 9/11?


Oh, my, Larry, are we now back to the 3-towers thing, the missile that hit the Pentagon thing, and the Zionists that set up controlled demolitions thing? You have come full circle in your mission.

Why is it no one believes you?

Reply
Feb 7, 2015 14:12:37   #
OldDoc Loc: New York
 
larrypayne wrote:
If you had replied to the members, the replies would be recorded for members to see. That is the purpose of a forum--to exchange opinions and ideas.

If you only communicate through PMs, you are defeating the purpose of the forum.

If you're against science denial, what do you think brought down the 3 Towers on 9/11?


Sigh...now I see the problem the others on this thread have with you. Facts don't matter, and when they get in the way you change the topic.

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