Ugly Hedgehog - Photography Forum
Home Active Topics Newest Pictures Search Login Register
General Chit-Chat (non-photography talk)
Covid Vaccine
Page <prev 2 of 4 next> last>>
Dec 3, 2020 19:43:45   #
davidv Loc: salt lake city utah
 
I wonder how the vaccine just treats the COVID-19, maybe it will cure us of all virus’s .

Reply
Dec 3, 2020 19:45:46   #
Bike guy Loc: Atlanta
 
davidv wrote:
I wonder how the vaccine just treats the COVID-19, maybe it will cure us of all virus’s .


No!
But wearing masks can decrease influenza and common colds transmissions.

Reply
Dec 3, 2020 19:55:27   #
Triple G
 
Bike guy wrote:
No!
But wearing masks can decrease influenza and common colds transmissions.


My doctor commented that ordinary flu cases are fewer than in past years and credits mask wearing.

Reply
 
 
Dec 4, 2020 05:46:53   #
daldds Loc: NYC
 
I am 85 years old. I was able to become a participant in the Astra Zeneca trial here in New York City. I did it with the hope that I would get the vaccine, not the placebo. Luckily I did receive the vaccine and now have antibodies. That does not mean that I intend to ignore all safety precautions… Masks, social distancing, etc.

The information to date suggests AZ‘s
vaccine is not as effective as the other two, but it is apparently at least as effective as the average flu shot is each year. Something is better than nothing.

I intend to get the other vaccine when it becomes available. I cannot understand how anyone would want to deny himself this protection.

Reply
Dec 4, 2020 07:58:33   #
Jimmy T Loc: Virginia
 
jerryc41 wrote:
I hope this doesn't get moved out of this section. Let's not make it political. In case you didn't know, Dolly Parton donated $1 million to Covid research, and that went to Moderna. I read that she is a millionaire, rather than a billionaire, because she has given so much money away.

From what I've been reading, the vaccines that have been developed seem to be good. I had my doubts at first, but when my time comes, I'll get the shot. There is no virus - dead or alive - in the vaccine. It simply trains your own immune system to recognize and fight the virus. It's not a miracle drug, and you might still get a mild case of Covid if you aren't careful, but it looks like a game changer.

Locally, our "Active" numbers have been rising by almost a hundred a day in my county. The infection rate for people being tested is also rising. Almost 5% of those tested are testing positive now. I'm staying home almost all the time, and my son has taken a leave of absence from work.

Good luck to all of you!
I hope this doesn't get moved out of this section.... (show quote)


Jerry:
I concur 100%
To all, be careful out there, stay safe & stay well!
Smile,
JimmyT Sends

Reply
Dec 4, 2020 08:05:44   #
BusterCrabbe Loc: Montreal
 
I am a scientist and work in the vaccine field. The soon to be approved vaccines are a mix, two are mRNA and one is a viral backbone vaccine. The first two are indeed new but this technology was mainly being developed in the cancer vaccine domain rather than as microbial disease vaccines. Same principle though. They work well as explained above but their biggest issue is that mRNA is inherently unstable and can be easily degraded...thus it needs to be kept cold to stop that. Very cold which brings in the logistics problem of having enough -80oC freezers around the country for transport and storage.
In my opinion, all of these vaccines are safe. Your only worry about this vaccine is that ...is it effective? So far the data has been fantastic (remember that normally, if a vaccine is 60% effective, that is considered very good). Luckily, we have had a lot of info with the other coronavirus issues (Sars and Mers) that preceded it so that helped a lot.
As to the argument that it normally takes 5-10 years to make a vaccine and this one is being made in less than a year so people worry about its safety not being properly looked at, what people do not realize that in non-pandemic years, the FDA in the US or Health Canada in Canada have many, many, many vaccines and biotherapeutics applications in front of them. With COVID, the shortcuts come a lot from prioritization and other biotherapeutic applications taking a backseat. As for safety, no shortcuts. Yes Pfizer and Moderna et al are asking for Emergency usage but be comforted by the fact that all phase trials were carried out properly as for any vaccine and will be safe. The questions usually posed (and which take a long time to answer) are after injection data like....how long does the protection last or do you need a booster. how often? Is it like the flu (every year) or like Tetanus (every ten years). This is something that is normally looked at in a normal vaccine application but that will only be answered as we go along. And that is ok. Save everyone first and we will sort that out later.

Reply
Dec 4, 2020 08:07:32   #
BusterCrabbe Loc: Montreal
 
davidv wrote:
I wonder how the vaccine just treats the COVID-19, maybe it will cure us of all virus’s .


Unfortunately, the vaccine is very specific. It may attenuate other coronavirus strains (remember Sars and Mers?) but not other viruses (Flu, Ebola etc etc).

Reply
 
 
Dec 4, 2020 08:07:46   #
jerryc41 Loc: Catskill Mts of NY
 
BusterCrabbe wrote:
I am a scientist and work in the vaccine field. The soon to be approved vaccines are a mix, two are mRNA and one is a viral backbone vaccine. The first two are indeed new but this technology was mainly being developed in the cancer vaccine domain rather than as microbial disease vaccines. Same principle though. They work well as explained above but their biggest issue is that mRNA is inherently unstable and can be easily degraded...thus it needs to be kept cold to stop that. Very cold which brings in the logistics problem of having enough -80oC freezers around the country for transport and storage.
In my opinion, all of these vaccines are safe. Your only worry about this vaccine is that ...is it effective? So far the data has been fantastic (remember that normally, if a vaccine is 60% effective, that is considered very good). Luckily, we have had a lot of info with the other coronavirus issues (Sars and Mers) that preceded it so that helped a lot.
As to the argument that it normally takes 5-10 years to make a vaccine and this one is being made in less than a year so people worry about its safety not being properly looked at, what people do not realize that in non-pandemic years, the FDA in the US or Health Canada in Canada have many, many, many vaccines and biotherapeutics applications in front of them. With COVID, the shortcuts come a lot from prioritization and other biotherapeutic applications taking a backseat. As for safety, no shortcuts. Yes Pfizer and Moderna et al are asking for Emergency usage but be comforted by the fact that all phase trials were carried out properly as for any vaccine and will be safe. The questions usually posed (and which take a long time to answer) are after injection data like....how long does the protection last or do you need a booster. how often? Is it like the flu (every year) or like Tetanus (every ten years). This is something that is normally looked at in a normal vaccine application but that will only be answered as we go along. And that is ok. Save everyone first and we will sort that out later.
I am a scientist and work in the vaccine field. Th... (show quote)



Reply
Dec 4, 2020 08:17:36   #
ltj123 Loc: NW Wisconsin
 
My two daughters and son-in-law are critical health workers, they'll be required to take vaccine during initial round of shots. I'll be able to see how they react to side effects before I'll be able to take vaccine. Then make my decision.
What bugs me is that the vaccine may be good for short period - 3 to 12 months....

Reply
Dec 4, 2020 10:26:53   #
TriX Loc: Raleigh, NC
 
BusterCrabbe wrote:
I am a scientist and work in the vaccine field. The soon to be approved vaccines are a mix, two are mRNA and one is a viral backbone vaccine. The first two are indeed new but this technology was mainly being developed in the cancer vaccine domain rather than as microbial disease vaccines. Same principle though. They work well as explained above but their biggest issue is that mRNA is inherently unstable and can be easily degraded...thus it needs to be kept cold to stop that. Very cold which brings in the logistics problem of having enough -80oC freezers around the country for transport and storage.
In my opinion, all of these vaccines are safe. Your only worry about this vaccine is that ...is it effective? So far the data has been fantastic (remember that normally, if a vaccine is 60% effective, that is considered very good). Luckily, we have had a lot of info with the other coronavirus issues (Sars and Mers) that preceded it so that helped a lot.
As to the argument that it normally takes 5-10 years to make a vaccine and this one is being made in less than a year so people worry about its safety not being properly looked at, what people do not realize that in non-pandemic years, the FDA in the US or Health Canada in Canada have many, many, many vaccines and biotherapeutics applications in front of them. With COVID, the shortcuts come a lot from prioritization and other biotherapeutic applications taking a backseat. As for safety, no shortcuts. Yes Pfizer and Moderna et al are asking for Emergency usage but be comforted by the fact that all phase trials were carried out properly as for any vaccine and will be safe. The questions usually posed (and which take a long time to answer) are after injection data like....how long does the protection last or do you need a booster. how often? Is it like the flu (every year) or like Tetanus (every ten years). This is something that is normally looked at in a normal vaccine application but that will only be answered as we go along. And that is ok. Save everyone first and we will sort that out later.
I am a scientist and work in the vaccine field. Th... (show quote)


👍👍 Well said.

Reply
Dec 4, 2020 10:39:14   #
tomad Loc: North Carolina
 
The physician group that my doctor is a part of ran a local segment of the Moderna trial and are also involved in the Johnson & Johnson trial. My doc sent out a note today letting everyone know their vaccine distribution plans. Round 1 to medical personnel, first responders, and nursing home residents and workers followed closely by round 1b to individuals with 2 or more conditions that make them more susceptible to serious or fatal infection. Then round 2 to everyone over 65, followed by round 3 to the general population. His practice has already stocked up on the -70 degree freezers required to keep some of the vaccines viable. I'll be near the front of the line when round 2 starts.

Reply
 
 
Dec 4, 2020 11:13:45   #
John_F Loc: Minneapolis, MN
 
This is a fundamental explanation that should get published in the newspapers. I am going tocopy and paste to my Facebook page in hopes it spreads more widely than here in the Hog.


David Martin wrote:
The public needs to know that the vaccines from Pfizer, Moderna and AstraZeneca are something entirely new: they are mRNA (messenger RNA) vaccines.

What is messenger RNA? mRNA is like a blueprint that tells a cell how to make a specific protein.

Why is this important? Traditional vaccines use dead or inactivated virus injected into a person, or they use a protein which has been isolated from the virus injected into a person, causing the immune system to form antibodies against the virus.

mRNA vaccines do not use a virus or a viral protein. Instead, they use a piece of laboratory-created messenger RNA, essentially a man-made synthetic copy of part of Covid-19's mRNA.

The mRNA vaccines "trick" the body's cells into making Covid-19's spike protein. The body then recognizes the spike protein as foreign, and makes antibodies against it. The mRNA vaccine may also stimulate other portions of our immune system (the innate immune system or the T cell immune system) in addition to the production of antibodies, potentially making them more effective than traditional vaccines.

mRNA vaccines are revolutionary because they let the recipient of the vaccine do the work of producing the viral protein that triggers the immune response. Time to develop such a vaccine, and cost to produce the vaccine, are significantly reduced.

There are unknowns: the true efficacy when given on a large scale, and the potential for undesirable side-effects. The Covid vaccines will be the first time mRNA vaccines have been approved for use. The population should understand that they are participating in something entirely new. Quite fitting for 2020.
The public needs to know that the vaccines from Pf... (show quote)

Reply
Dec 4, 2020 11:36:35   #
steve Loc: Iowa
 
jerryc41 wrote:
I hope this doesn't get moved out of this section. Let's not make it political. In case you didn't know, Dolly Parton donated $1 million to Covid research, and that went to Moderna. I read that she is a millionaire, rather than a billionaire, because she has given so much money away.

From what I've been reading, the vaccines that have been developed seem to be good. I had my doubts at first, but when my time comes, I'll get the shot. There is no virus - dead or alive - in the vaccine. It simply trains your own immune system to recognize and fight the virus. It's not a miracle drug, and you might still get a mild case of Covid if you aren't careful, but it looks like a game changer.

Locally, our "Active" numbers have been rising by almost a hundred a day in my county. The infection rate for people being tested is also rising. Almost 5% of those tested are testing positive now. I'm staying home almost all the time, and my son has taken a leave of absence from work.

Good luck to all of you!
I hope this doesn't get moved out of this section.... (show quote)


Thanks for info Jerry. I wait to see if ppl have severe adverse reactions 1st.

Reply
Dec 4, 2020 11:50:38   #
daldds Loc: NYC
 
I can give you a “series of one case”response. Four weeks ago I received the first of two Astra Zeneca vaccine injections in their trial. I had absolutely no reaction whatsoever (which disappointed me because I thought I had gotten the saline).

Three days ago I received the second injection. After 24 hours I had injection site tenderness, which lasted through now, but is just about gone. It did not inhibit me in anyway, nor did I need any pain relief. No other reaction, BTW.

The reason I know I received a vaccine is because I had my annual exam a couple of days ago and had asked that an antibody test be included. The double blind study people were not going to tell me. I have antibodies.

Reply
Dec 4, 2020 12:53:06   #
David Martin Loc: Cary, NC
 
daldds wrote:
I had absolutely no reaction whatsoever (which disappointed me because I thought I had gotten the saline)... I have antibodies.

Perhaps you were in the cohort that only received half a dose the first time?

Reply
Page <prev 2 of 4 next> last>>
If you want to reply, then register here. Registration is free and your account is created instantly, so you can post right away.
General Chit-Chat (non-photography talk)
UglyHedgehog.com - Forum
Copyright 2011-2024 Ugly Hedgehog, Inc.