rehess Loc: South Bend, Indiana, USA

Does the V500 not have software that looks for media laid out according to a pattern set by the holders??

Bunko.T Loc: Western Australia.

I left off the guides for slides or film, even the other guide for old b&w negs. I positioned my negs on the glass, lined up with edge of scan strip. You have to remove the faux pad to expose the light strip in lid.
My old b&w negs were the old 127 size, which were wider than the scan strip, but I had to sacrifice a small strip of foreground or sky. This was no problem, just made them look like a pano.
About 100 of these images were of historical significance to our state timber industry of the early 1900s, so I had them scanned professionally to have a copy of the full sized scans before I donate them to the national archives.

Architect1776 Loc: In my mind

For odd shapes I made holders out of Black Matt board so no part of the image was lost.

adamsg Loc: Chubbuck, ID

I have an Epson Perfection V600 Photo. It works tremendously well on prints, slides and negatives. Color correction, dust removal and a very wide range of pixels have made this invaluable to me as I digitize the proceeds of four decades of film photography.

hpucker99 Loc: Anchorage, Alaska

I took about 300 35mm slides to Costco earlier this summer and then spent time in Lightroom/Photoshop cleaning them up. Their cost is about 40 cents a slide. It was mostly a trial run and I was pleased with the results. At first I was disappointed in some of the scans until I look at the slides, they weren't that good to begin with.

rehess Loc: South Bend, Indiana, USA

And that is the central issue - quality of the original media. I have a Nikon LS-2000 which can make up to 16 scans of each line, each scan from a different angle, which allows it to use parallax to fix most errors other than those imbedded into the emulsion layer.