Like depth of field, diffraction does not happen suddenly. We calculate that it happens once the diameter of the airy disk exceeds the diameter of the circle of confusion. The difference between being just under or just over is not something you will be able to see. These two diameters may seem arbitrary but they are based on sound principles. Both terms are described in depth on their site and elsewhere on the Internet and they are easy to look up.
Open the
Diffraction Limit Calculator and click on show advanced to see the relationships among the six parameters that affect diffraction:
Max Print Dimension Diffraction is more apparent in a larger print if you keep the viewing distance the same.
Viewing distance Diffraction is less apparent if you view the same print from further away.
Eyesight You are more likely to see diffraction if your eyesight is above average.
Digital resolution MP You are more likely to see diffraction if you view an image on the screen at 100%.
Camera Type (sensor or film format) Diffraction is worse for smaller sensors and film sizes and almost invisible in medium or large format film.
Aperture Diffraction is more likely to be seen at smaller apertures if the image contains sharp edges and detail.
All of the calculations assume that
you are not cropping the image.
If you keep the viewing distance proportional to the maximum print dimension appearance of diffraction is not affected. For example, a 20 inch print viewed from 50 cm has the same apparent diffraction as a 10 inch print viewed from 25 cm.
In Figure One you can see that a normal 8x10 inch print viewed from a normal viewing distance of 25 cm (about 10 inches) with normal eyesight, an aperture of f/16 does not produce visible diffraction. The 24x36 mm sensor image is magnified about 7x to a width of 10 inches (254 mm).
In Figure Two the same image is magnified to 100%. At 300 dpi makes a 20 inch wide print, a magnification of about 14x. In this case, f/16 is too small when viewed from 10 inches but not when viewed from 20 inches.
If the image is cropped by a factor of two (discarding 75% of the information) to a width of 10 inches, the magnification would still be 14x and the diffraction would also be visible at f/16. If you plan to crop the image because your focal length was too short you need to take this into account.